Officers are concerned for the welfare of a 25-year-old woman who has been reported missing from Stroud.
Megan Hopkins was last seen on Vicarage Close in Cashes Green yesterday afternoon and it is believed that she has travelled to the Brixton area of London via public transport.
She is described as being 5ft 9ins tall, of a large build and has shoulder length light brown hair.
Megan wears glasses and is believed to be wearing a blue Christmas patterned shirt, a red and gold neck tie, black jogging bottoms and a green coat with a fur collar.
She has severe learning disabilities and is considered to be very vulnerable.
Anyone who has seen Megan or has any information on her whereabouts is urged to call 101 quoting incident 441 on December 19.