A 19-year-old man has been seriously hurt in a stabbing, which left another with an injury to his hand.
The men, both aged 19, were attacked in Clarence Street in the centre of Gloucester shortly before 02:25 GMT, police said.
They were taken to hospital for treatment. The street remains cordoned off while investigations continue.
A 29-year-old man and 19-year-old woman have been arrested and remain in police custody.