Police were called after a car hit a pedestrian at Salmon Springs on the A46 between Stroud and Painswick at around 10am.
Pictures of the scene show drivers attempting to drive past the police barriers.
The Painswick Road is still expected to remain closed in both directions for a number of hours.
Drivers should plan accordingly.
Road closures are in place near Stroud following a serious collision. We were called to the collision between a car and a pedestrian outside Salmon Springs on the A46 at around 10am today. The road is expected to remain closed for some time. Please plan your route accordingly. pic.twitter.com/K5uAZ8M2gH
— Glos Police (@Glos_Police) October 11, 2022