Resurfacing work is due to be carried out on the A429 Malmesbury bypass.
Work will be undertaken from 7pm-6am between Thursday, November 25 and Thursday, December 2.
However, residents have been warned that this may be extended due to uncontrollable circumstances such as plant breakdowns, if weather conditions are unfavourable, or the need for additional repairs is discovered once the work has started.
The work involves repairs to the existing carriageway, the installation of new road markings and the adjustment of surface ironwork.
There will be points where vehicular access will not be possible as plant may be obstructing the road or material may be newly laid which residents will not be able to drive over, as early trafficking could lead to premature failure.
It is recommended to residents and businesses that if works are being undertaken in the vicinity of their property to speak to the workforce in advance to ask if there will be any restrictions with regards to access.
Work is being carried out between the Priory Roundabout and the Whychurch Roundabout.